When in Rome, do as the Romans: Surround yourself with art and history as you eat delicious pasta dishes. Between meals, visit the Vatican, the home of the Catholic Church and a separate country within the city of Rome. Gaze up into the floating dome at the Pantheon, which was built in 27 B.C. Then head over to the Colosseum, an amphitheater that dates back to A.D. 80 and has secret passageways that tourists now explore. (MURAT TANER—GETTY IMAGES)